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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2003 2
2004 2
2006 2
2007 3
2008 2
2009 2
2010 1
2011 3
2012 2
2013 5
2014 9
2015 12
2016 18
2017 9
2018 11
2019 18
2020 14
2021 23
2022 14
2023 9
2024 4

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144 results

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Page 1
Polymorphisms of the IL12B, IL1B, and TNFA genes and susceptibility to asthma.
Padrón-Morales J, Sanz C, Dávila I, Muñoz-Bellido F, Lorente F, Isidoro-García M. Padrón-Morales J, et al. J Investig Allergol Clin Immunol. 2013;23(7):487-94. J Investig Allergol Clin Immunol. 2013. PMID: 24654313 Free article.
The IL1B TT haplotype (3962T and -511T) was also associated with atopy and moderate-persistent asthma. CONCLUSION: Our data show that the presence of SNPs in IL12B, TNFA, and IL1B was significantly associated with asthma, atopy, and severity of asth …
The IL1B TT haplotype (3962T and -511T) was also associated with atopy and moderate-persistent asthma. CONCLUSION: Our data sh …
Single-cell analysis reveals alterations in cellular composition and cell-cell communication associated with airway inflammation and remodeling in asthma.
Yu X, Li L, Cai B, Zhang W, Liu Q, Li N, Shi X, Yu L, Chen R, Qiu C. Yu X, et al. Respir Res. 2024 Feb 5;25(1):76. doi: 10.1186/s12931-024-02706-4. Respir Res. 2024. PMID: 38317239 Free PMC article.
The specific interactions between immune and stromal cells, crucial for asthma pathogenesis, remain unclear. This study aims to determine the key cell types and their pathological mechanisms in asthma through single-cell RNA sequencing (scRNA-seq). ...In particular, …
The specific interactions between immune and stromal cells, crucial for asthma pathogenesis, remain unclear. This study aims to deter …
Endoplasmic reticulum-unfolded protein response signalling is altered in severe eosinophilic and neutrophilic asthma.
Pathinayake PS, Waters DW, Nichol KS, Brown AC, Reid AT, Hsu AC, Horvat JC, Wood LG, Baines KJ, Simpson JL, Gibson PG, Hansbro PM, Wark PAB. Pathinayake PS, et al. Thorax. 2022 May;77(5):443-451. doi: 10.1136/thoraxjnl-2020-215979. Epub 2021 Sep 11. Thorax. 2022. PMID: 34510013
These markers were also assessed in established eosinophilic and neutrophilic murine models of asthma. RESULTS: Our results demonstrate increased ER stress and UPR pathways in asthma and these are related to clinical severity and inflammatory phenotypes. ...CONCLUSI …
These markers were also assessed in established eosinophilic and neutrophilic murine models of asthma. RESULTS: Our results demonstra …
Six gene and TH2 signature expression in endobronchial biopsies of participants with asthma.
Sánchez-Ovando S, Baines KJ, Barker D, Wark PA, Simpson JL. Sánchez-Ovando S, et al. Immun Inflamm Dis. 2020 Mar;8(1):40-49. doi: 10.1002/iid3.282. Epub 2020 Jan 5. Immun Inflamm Dis. 2020. PMID: 31903716 Free PMC article.
Correlations with clinical and cellular characteristics were performed, and receiver operating characteristic was utilized to assess signatures' ability to predict asthma from HC and inflammatory phenotypes. RESULTS: Gene expression of DNASE1L3 (P = .045) was upregulated i …
Correlations with clinical and cellular characteristics were performed, and receiver operating characteristic was utilized to assess signatu …
Aspirin-Exacerbated Respiratory Disease Polymorphisms; a review study.
Fathollahpour A, Abyaneh FA, Darabi B, Ebrahimi M, Kooti W, Kalmarzi RN. Fathollahpour A, et al. Gene. 2023 Jun 20;870:147326. doi: 10.1016/j.gene.2023.147326. Epub 2023 Apr 1. Gene. 2023. PMID: 37011853 Review.
Aspirin exacerbated respiratory disease (AERD) is a condition caused by increased bronchoconstriction in people with asthma after taking aspirin or another NSAID. Molecular analysis of the human genome has opened up new perspectives on human polymorphisms and disease. ...W …
Aspirin exacerbated respiratory disease (AERD) is a condition caused by increased bronchoconstriction in people with asthma after tak …
Interleukin 1beta polymorphism and serum level are associated with pediatric asthma.
Sobkowiak P, Wojsyk-Banaszak I, Kowalewska M, Wasilewska E, Langwiński W, Kycler Z, Skibińska M, Bręborowicz A, Jassem E, Szczepankiewicz A. Sobkowiak P, et al. Pediatr Pulmonol. 2017 Dec;52(12):1565-1571. doi: 10.1002/ppul.23893. Epub 2017 Oct 16. Pediatr Pulmonol. 2017. PMID: 29034996
We hypothesized that polymorphic variants of interleukin 1 genes may play a role in childhood asthma risk. The aim of this study was to investigate if IL-1alpha and beta polymorphism is associated with asthma in a pediatric population and if the genotype affects its …
We hypothesized that polymorphic variants of interleukin 1 genes may play a role in childhood asthma risk. The aim of this study was …
The ORMDL3 Asthma Gene Regulates ICAM1 and Has Multiple Effects on Cellular Inflammation.
Zhang Y, Willis-Owen SAG, Spiegel S, Lloyd CM, Moffatt MF, Cookson WOCM. Zhang Y, et al. Am J Respir Crit Care Med. 2019 Feb 15;199(4):478-488. doi: 10.1164/rccm.201803-0438OC. Am J Respir Crit Care Med. 2019. PMID: 30339462 Free PMC article.
RATIONALE: Polymorphisms on chromosome 17q21 confer the major genetic susceptibility to childhood-onset asthma. Risk alleles positively correlate with ORMDL3 (orosomucoid-like 3) expression. ...CONCLUSIONS: The results show ORMDL3 has pleiotropic effects during cellular in …
RATIONALE: Polymorphisms on chromosome 17q21 confer the major genetic susceptibility to childhood-onset asthma. Risk alleles positive …
The Alleviating Impacts of Quercetin on Inflammation and Oxidant-antioxidant Imbalance in Rats with Allergic Asthma.
Rajizadeh MA, Bejeshk MA, Doustimotlagh AH, Najafipour H, Eftekhari M, Mahmoodi M, Azizi M, Rostamabadi F, Pourghadamyari H. Rajizadeh MA, et al. Iran J Allergy Asthma Immunol. 2023 Apr 30;22(2):138-149. doi: 10.18502/ijaai.v22i2.12675. Iran J Allergy Asthma Immunol. 2023. PMID: 37496407 Free article.
Rats were divided into 4 groups: control, asthma+vehicle (Receieved normal saline), asthma+dexamethasone, and asthma+quercetin. ...The results showed that quercetin reduced Gata3, Tnf, Tgfb1, Il1b, and Acta2 gene expression and increased Tbx21 gene exp …
Rats were divided into 4 groups: control, asthma+vehicle (Receieved normal saline), asthma+dexamethasone, and asthma+qu …
Anti-inflammatory deficiencies in neutrophilic asthma: reduced galectin-3 and IL-1RA/IL-1beta.
Gao P, Gibson PG, Baines KJ, Yang IA, Upham JW, Reynolds PN, Hodge S, James AL, Jenkins C, Peters MJ, Zhang J, Simpson JL. Gao P, et al. Respir Res. 2015 Jan 24;16(1):5. doi: 10.1186/s12931-014-0163-5. Respir Res. 2015. PMID: 25616863 Free PMC article.
RESULTS: Sputum gal-3 (median, (q1,q3)) was significantly reduced in neutrophilic asthma (183 ng/mL (91,287)) compared with eosinophilic (293 ng/mL (188,471), p = 0.021) and paucigranulocytic asthma (399 ng/mL (213,514), p = 0.004). The gal-3/gal-3BP ratio and IL-1R …
RESULTS: Sputum gal-3 (median, (q1,q3)) was significantly reduced in neutrophilic asthma (183 ng/mL (91,287)) compared with eosinophi …
Determination of the effects of advanced glycation end products receptor polymorphisms and its activation on structural cell responses and inflammation in asthma.
Birben E, Şahiner ÜM, Kalaycı CÖ. Birben E, et al. Turk J Med Sci. 2023 Feb;53(1):160-170. doi: 10.55730/1300-0144.5569. Epub 2023 Feb 22. Turk J Med Sci. 2023. PMID: 36945930 Free PMC article.
BACKGROUND: Advanced glycation end products receptor (RAGE) is a pattern recognition receptor which attracted attention in chronic airway diseases recently. This study aimed to determine the association of RAGE with asthma and the cellular responses resulting from RAGE sig …
BACKGROUND: Advanced glycation end products receptor (RAGE) is a pattern recognition receptor which attracted attention in chronic airway di …
144 results